Dosage ; see below
Combinations ; - see below
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| POR 8 | Ferring Pharmaceuticals | MacNaughton Limited | 5iu | 5ml | Injection | per vial | KES 5,319.00 |
| Ornipressin More info | |
|---|---|
| Mode Of Action | Polypeptides with a potent and specific constrictor effect on microcirculation and veins |
| Drug Indication | To induce ischaemia and haemostasis at the site of an operation. It may be used with general anaesthetics which are usually not compatible with adrenaline; e.g. halothane, without fear of precipitating cardiac arrhythmias. |
| Precautions | Some absorption may occur from local application leading to systemic vasoconstriction. A rise in blood pressure may occur in some patients. Caution is therefore indicated in conditions in which a rise in blood pressure would be medically undesirable. Anginal symptoms may be precipitated in patients with ischaemic heart disease. |
| Side Effects | It is generally well tolerated; facial or general pallor; a rise (or occasionally fall) in blood pressure, cardiac arrhythmias, anginal pain, increased perspiration and increased bowel motility. |
| Dosage | Usually 5 IU is diluted in 30 mL of physiological saline (max. dose for tissue infiltration is 5 IU). Gynaecological surgery and laparotomies, more dilute solutions, e.g. 5 IU in 50 or 60 mL physiological saline are used. For ENT surgery more concentrated solutions, 5 IU in 20 mL physiological saline may be used. |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Vasoconstrictor sympathomimetics |